منابع مشابه
Mechanism of Action of Transketolase
For detailed studies on the mode of action of an enzyme a readily available source and a convenient method of preparation are of distinct advantage. Accessible sources such as bakers’ yeast (1) and spinach leaves (2) have, therefore, been used for large-scale preparations of transketolase in spite of the fact that extracts of Escherichia coli, in which the cleavage of ribose-5-P to triose-P was...
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SUMMARY The foliowing cardiac effects may be attributed to thyroxin: 1-Thyroxin augments all anaerobic processes in the body includ::ng the heart, and decreases the glycogen content of the heart ( 1, 2, 5, 27). The resistance of the heart to anoxia is increased in hyperthyroidism ( 25). 2- Thyroxin influences the cardiac weight and prevents cardiac atrophy (3, 8, 10, 11, 19, 20, 21, 30...
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Polypyrrole-chitosan nanocomposite (PPy-CTN) was synthesized by dispersion polymerization of PPy in presence of CTN. Preparation of spherical PPy nanoparticles that were successfully covered with a thin layer of chitosan was confirm by transmission electron microscopy (TEM) technique. Characterization techniques also revealed the presence of CNT in the polymer matrix and its presence was confir...
متن کاملMechanism of action of transketolase. I. Properties of the crystalline yeast enzyme.
For detailed studies on the mode of action of an enzyme a readily available source and a convenient method of preparation are of distinct advantage. Accessible sources such as bakers’ yeast (1) and spinach leaves (2) have, therefore, been used for large-scale preparations of transketolase in spite of the fact that extracts of Escherichia coli, in which the cleavage of ribose-5-P to triose-P was...
متن کاملMechanism-Based Studies of the Active Site-Directed Inhibition and Activation of Enzyme Transketolase
Derivatives of phenyl-keto butenoic acids have been reported to be inhibitors of pyruvate decarboxylase, (PDC). The inhibition of transketolase, a thiamine requiring enzyme such as PDF, by meta nitrophenyl derivative of 2-oxo-3-butenoic acid (MNPB) is reported here. These studies indicate that the inhibitor binds to the enzyme at the active site. A two-step inhibition was observed, first th...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1961
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)64277-2